Savene® is indicated for the treatment of anthracycline extravasation
The extravasation of cytotoxic agents is a devastating complication of chemotherapy. It is defined as the unintentional installation or leakage into the perivascular or subcutaneous spaces during administration
The event is relatively rare but potentially devastating and very disquieting. Accidental extravasation of anthracyclines may cause severe, progressive tissue damage that may progress over days and weeks. Symptoms often seen are redness, swelling, pain, increased risk of infection, joint destruction, lesions of nerves, and permanent dysfunctional and cosmetic changes of the involved area
If an anthracycline extravasation occurs during treatment with anthracyclines the healthcare professional should initiate treatment with Savene® as soon as possible after the accident in order to minimise the negative consequences of the extravasation