Current treatment approaches

None of the conventional treatments of extravasation (dimethyl sulfoxide, hydrocortisone, cold packs, limb elevation, flushing, etc.) have any proven benefits in reducing the tissue damage caused by anthracycline extravasation4,5


When using conventional treatments the outcome of anthracycline extravasation is typically poor, with many patients experiencing serious sequelae as a result of the extravasation or subsequent surgery


Surgery and its associated recovery time, plus the risk of infection, may lead to delays in scheduled cancer chemotherapy


None of the non-surgical methods has shown proven efficacy in biopsy verified cases of anthracycline extravasation7,10