None of the conventional treatments of extravasation (dimethyl sulfoxide [DMSO], hydrocortisone, cold packs, limb elevation, flushing, etc.) have any proven benefits in reducing the tissue damage caused by anthracycline extravasation
When using conventional treatments the outcome of anthracycline extravasation is typically poor, with many patients experiencing serious sequelae as a result of the extravasation or subsequent surgery
Surgery and its associated recovery time, plus the risk of infection, may lead to delays in scheduled cancer chemotherapy
None of the non-surgical methods has shown proven efficacy in biopsy verified cases of anthracycline extravasation
