The information on this page is provided for patients who have been given SAVENE® (dexrazoxane). The information is not intended to substitute the advice given by your healthcare professional. Consult your doctor for all questions you have concerning your treatment.

SAVENE® contains the active substance dexrazoxane which is used to treat anthracycline extravasation in adults. Anthracyclines are a class of drugs used in cancer chemotherapy.

Most anti-cancer medicines are administered intravenously (into a vein). Occasionally an accident may occur and the medicine is infused outside the vein and into the surrounding tissue or leaks from the vein into the surrounding tissue. This event is called extravasation. Extravasation is a serious complication as it can cause severe tissue damage. SAVENE® is used to treat anthracycline extravasation in adults. It can reduce the amount of tissue damage caused by anthracycline extravasation.

For more information about your treatment with SAVENE®, please refer to the package leaflet which is included in the pack and written for patients. A copy of this package leaflet for patients in the UK is available at the Electronic Medicines Compendium by clicking the link below.

Savene Patient Leaflet


If you are experiencing or get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet.

In the UK, you can also report side effects directly via the Yellow Card Scheme at https://yellowcard.mhra.gov.uk/.

By reporting side effects, you help provide more information on the safety of medicines.